MOTS-c — Buy in Canada

What is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded within the mitochondrial genome and discovered in 2015 by researchers at USC. It is one of the first identified mitochondria-derived peptides (MDPs) and acts as a metabolic hormone, regulating glucose metabolism, insulin sensitivity, and cellular stress responses. Circulating MOTS-c levels decline significantly with age, making it a compelling focus in longevity and metabolic research.

VELTRIDE supplies MOTS-c 10mg lyophilized powder at ≥98% HPLC-verified purity with Certificate of Analysis, shipped discreetly across Canada from West Kelowna, BC. MOTS-c is one of the most cutting-edge peptides in the longevity research space, attracting growing interest from Canadian researchers studying metabolism, aging, and exercise physiology.

Research Highlights

• Encoded in mitochondrial genome — first identified mitochondria-derived peptide
• Activates AMPK — studied for insulin sensitivity and glucose metabolism
• Age-related MOTS-c decline — restoration experiments in aged animal models
• Exercise-mimetic effects — activates metabolic pathways similar to physical activity
• Reduces obesity and insulin resistance in high-fat diet rodent models
• Nuclear translocation under stress — regulates gene expression for cellular protection
• Studied for longevity benefits in centenarian and age-related disease research

Stacks Well With

MOTS-c is studied alongside NAD+ for comprehensive mitochondrial longevity research. Epithalon complements MOTS-c for multi-pathway aging research combining telomere and metabolic endpoints. Tesamorelin pairs well for metabolic syndrome research.

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